Drosophila CRISPRi/CRISPRa Service

Cas9 is a powerful DNA-binding unwinding protein that may assists other proteins turn transcription on or off dynamically and quantitatively to regulate targeted gene expression. CRISPRi/CRISPRa is a more flexible tool, especially in vivo that effectively prevents the cytotoxicity caused by double-stranded DNA breaks, and compensates for the limitations of CRISPR/Cas9 permanent knockout of essential genes and long non-coding RNAs, etc.  Learn more: Drosophila CRISPRi/CRISPRa